Professor Brian D. Smith

Supporting strategists in the life sciences

“

Who I am

I research, teach and write about strategising in pharma and medtech and I help you to strategise and execute better than your competitors.

As a thought leader, I’ve published hundreds of articles and books. In two decades in the industry as a scientist and marketer, then two decades as an academic, author and advisor, I’ve helped hundreds of life science companies to achieve their goals.

If you share my fascination with strategy in the life sciences, let’s chat.

“

Who I am

I research, teach and write about strategising in pharma and medtech and I help you to strategise and execute better than your competitors.

As a thought leader, I’ve published hundreds of articles and books. In two decades in the industry as a scientist and marketer, then two decades as an academic, author and advisor, I’ve helped hundreds of life science companies to achieve their goals.

If you share my fascination with strategy in the life sciences, let’s chat.

How I can help you

Creating strong strategy

Your job is to create and execute strong strategy.

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Validating your strategy

You need to know that your strategy will work.

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Anticipating the market

You must anticipate your market, not react to it.

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Mentoring strategists

Strong strategists must grow and develop.

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Aligning strategy and culture

Your culture must amplify your strategy.

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Creating market insight

Strong strategists know what their competitors don’t.

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Training cross-functional teams

Strategizing is a team game.

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Enhancing your meetings

Meetings and conferences must add value.

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Creating value beyond the product

Your product is only a fraction of the value you create.

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Transforming your business model

Your business model must fit your market environment and goals.

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My published work

Browse my hundreds of articles, about strategy in the life sciences and ask for any you want.
Or click on any of curated collections below.

Cross-functional implementation

Strategy without execution is just a fantasy. These articles cover the human side of strategy execution through cross-functional teams.

Leadership in
the life sciences

The life sciences industry is not like any other. These articles explain how its leaders adapt to their unique context.

Becoming a
strategy expert

True strategy expertise is rare. These articles cover the three things you must master to achieve it.

Making strong strategies

Strategy is simple but not easy. These articles define what strong strategies look like and how they are made.

Industry evolution

The life sciences industry is a complex, adaptive ecosystem. These articles explain its evolution and how to manage your own.

Strategy’s human side

Strategy is a social process. These articles explain the cultural and behavioural issues that can strangle or supercharge your strategy.

Cross-functional implementation

Strategy without execution is just a fantasy. These articles cover the human side of strategy execution through cross-functional teams.

Becoming a
strategy expert

True strategy expertise is rare. These articles cover the three things you must master to achieve it.

Industry evolution

The life sciences industry is a complex, adaptive ecosystem. These articles explain its evolution and how to manage your own.

Leadership in
the life sciences

The life sciences industry is not like any other. These articles explain how its leaders adapt to their unique context.

Making strong strategies

Strategy is simple but not easy. These articles define what strong strategies look like and how they are made.

Strategy’s human side

Strategy is a social process. These articles explain the cultural and behavioural issues that can strangle or supercharge your strategy.

My book seminars

My online book seminars let your team learn quickly and easily from my industry-specific research. Each seminar:
Summarises one book’s key points | Includes discussion | Take only 2 hours | Includes signed books
If you want your team to understand your industry better, let’s chat.

My latest work


2026.10.15.

Lilly Isn’t Reinventing, It’s Speciating

Why “the pharma business model” no longer means anything

This Substack article argues that Eli Lilly is not reinventing itself, but speciating, adding new business models alongside its traditional ones as the life sciences industry adapts to distinct market ‘habitats.’ Drawing on long-term research into industry evolution, it explains why firms now operate multiple species of business model under one roof, why capabilities must diverge as environments diverge, and how leaders can guide their own directed evolution rather than rely on slow, wasteful trial-and-error.

Request the PDF. 


2026.10.10.

Leading Through Complexity

Strengthening strategic judgement under uncertainty

The third article examines behavioural strategy, the discipline that helps leadership teams counter the predictable distortions of judgement that arise in complex, ambiguous environments. It explains how framing, challenge and calibration improve descision quality when evidence is incomplete, and how disciplined decision hygiene becomes a source of competitive advantage in life sciences.

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2026.09.30

Leading Through Platforms

Competing in an era beyond products

The second article explores platform strategy; how repeatable technological architectures can create advantage only when bounded, disciplined and anchored in customer value. It shows why platforms can stabilise portfolios in VUCA markets and why, without strategic governance, they become expensive distractions that amplify volatility rather than dampen it.

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2026.09.14.

Leading Through Turbulence

How dynamic capabilities enable adaptation to VUCA markets

The first article in the four-part series introduces dynamic capabilities, the sensing, seizing and reconfiguring routines that allow life sciences firms to adapt when volatility, uncertainty, complexity and ambiguity are the norm. It explains why some organisations evolve and thrive while others stall, and how leaders can diagnose and strengthen their own adaptive capacity.

Request the PDF. 

Contact me

If you share my fascination with the life sciences industry and how pharma and medtech strategies and business models are evolving, then I'd love to chat.

You don't need to fill in a form, speak to an assistant or give me your life story.

Just click here.

Your mail will come directly to me and I'll reply with times when I'm free.

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